1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the treatment method of several myeloma. Its synthesis or research is essential for making sure the purity and protection on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor inside the synthesis of abiraterone acetate, a drug Employed in the remedy of prostate cancer by inhibiting androgen creation.
Imatinib Intermediate (CAS NO. 152460-10-one): A critical compound during the synthesis of imatinib, a drug that targets specific types of cancer, like Continual myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats many cancers such as breast, lung, and prostate cancer.
two. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are intermediates within the synthesis of gemcitabine, an anti-most cancers drug. Their review is important for optimizing the production system and making certain higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to treat breast most cancers, and these intermediates are involved with its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the cure of breast most cancers. Numerous intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug efficient in treating cancers for instance ovarian, breast, and lung most cancers.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug used in the treatment method of colorectal most cancers and small cell lung cancer.
3-Amino-1-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved in the synthesis of adamantane derivatives, which have different programs, which include antiviral Attributes.
Vildagliptin Intermediates: Employed in the creation of vildagliptin, an oral drug for type two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of varied gluconic acid derivatives, which might be Employed in food items, pharmaceutical, and industrial apps.
Canagliflozin CAS NO.61259-48-1 Intermediate two: A precursor while in CAS NO. 417721-36-9 the synthesis of canagliflozin, a medication applied to control type two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).